Health research is diverse and varied and covers a spectrum from basic research to applied research. The production of new therapeutic compounds, for example, begins at the laboratory bench (basic) and proceeds through rigorous testing in clinical settings (applied) before they can be widely used in regular practice. The purpose of this editorial, by Melissa Simpson, DVM, PhD, Veterinary Epidemiologist at Morris Animal Foundation, is to discuss details about the types of studies that fall under the umbrella of applied research, including their advantages and limitations, and their utility in advancing animal health.