The protozoan parasite Cryptosporidium parvum is widespread in the environment and is well documented as a major cause of neonatal enteritis in farm livestock, particularly calves, which are considered to be the main reservoirs of the parasite. With no vaccine or cure currently available, C. parvum can cause serious disease, production losses and deaths in neonatal calves and occasionally in lambs. Beth Wells at Moredun Research Institute explores a One Health approach to solutions in Cryptosporidium control, outlining the management options available.