The 2025 harvest presented region-specific challenges in feed safety across Europe, the United States and Canada, with significant implications for livestock health and productivity. Over 2,000 new-crop samples were analysed globally, revealing a complex profile of multi-mycotoxin contamination. These findings emphasise the importance of proactive, evidence-based feed risk management and the need to understand both mycotoxin prevalence and co-occurrence in order to safeguard animal performance.